One of the world's most common artificial sweeteners is set to be declared a possible carcinogen next month by a leading global health body, according to two sources with knowledge of the process, pitting it against the food industry and regulators.
Oh my fuck. I hate news stories like this. Aspartame falls into the same cancer risk category as eating red meat sometimes and being kinda lazy. A rigorous systematic review was conducted of dozens of studies of aspartame and they did not find a plausible biologic mechanism by which aspartame could cause cancer. Epidemiologically, it’s vaguely correlated, not causative of cancer.
Also, in the Reuters article it notes that a 132-lbs adult would have to drink 12 to 36 cans of diet coke a day for the dose/exposure to become relevant to the risk they’re talking about. This article is talking about one study that is at odds with the systematically reviewed data from 40 human observational studies, 12 experimental animal studies, and 1360 assay/experimental end points to look for the supposed link.
Being lazy is vaguely kinda sorta correlated with cancer… but that doesn’t account for the fact that humans who are regularly active are also less likely to make other lifestyle choices that are more significantly tied to cancer like smoking and drinking.
This is the problem with a lot of population based studies. Obesity is linked with a lot of health problems like cardiovascular disease, but only some aspects of cardiovascular disease have causative links to obesity and others are sequelae of other factors that tend to be associated with obesity. For example, extra weight/adipose puts more stress on your heart by there just being more body mass to deliver blood to and more oxygen demand from muscles to just physically move the weight around (also a cause of joint problems)… but it’s the poor diet full of cholesterol that clogs up the arteries (aka atherosclerosis) causing myocardial infarction (heart attack).
Oh my fuck. I hate news stories like this. Aspartame falls into the same cancer risk category as eating red meat sometimes and being kinda lazy. A rigorous systematic review was conducted of dozens of studies of aspartame and they did not find a plausible biologic mechanism by which aspartame could cause cancer. Epidemiologically, it’s vaguely correlated, not causative of cancer.
Also, in the Reuters article it notes that a 132-lbs adult would have to drink 12 to 36 cans of diet coke a day for the dose/exposure to become relevant to the risk they’re talking about. This article is talking about one study that is at odds with the systematically reviewed data from 40 human observational studies, 12 experimental animal studies, and 1360 assay/experimental end points to look for the supposed link.
https://www.sciencedirect.com/science/article/pii/S0278691522007475#sec5
Wait being lazy cases cancer? I’m in a lot of trouble then
Being lazy is vaguely kinda sorta correlated with cancer… but that doesn’t account for the fact that humans who are regularly active are also less likely to make other lifestyle choices that are more significantly tied to cancer like smoking and drinking.
This is the problem with a lot of population based studies. Obesity is linked with a lot of health problems like cardiovascular disease, but only some aspects of cardiovascular disease have causative links to obesity and others are sequelae of other factors that tend to be associated with obesity. For example, extra weight/adipose puts more stress on your heart by there just being more body mass to deliver blood to and more oxygen demand from muscles to just physically move the weight around (also a cause of joint problems)… but it’s the poor diet full of cholesterol that clogs up the arteries (aka atherosclerosis) causing myocardial infarction (heart attack).