One day a coworker of mine was walking into our huge office building and thought he saw a mitten on the ground of the lobby. When he picked it up it was actually a pair of lacy women’s underwear. Ostensibly it fell out of someone’s gym bag or got caught in their pant leg in the laundry and dislodged there. He drops it immediately and comes into the office. He doesn’t mention this to anyone.

Two hours later the main receptionist comes in with the underwear in front of our whole group and says she saw him drop these this morning and she wants to return them. He’s denying the whole thing and at this point none of us have the previous context and all locked in to the conversation and silent laughing. She says, “We just want to give these back in case they have sentimental value!” and the the whole group is dying laughing now. He eventually convinces her he isn’t interested in a stranger’s underwear (which she bare handing) to which she says she’ll keep them in case he changes his mind (???).

It’s been 5 years and it gets brought up nearly daily

Just listened to it and god she is amazing. Great recommendation!

If you want to hear a surf rock instrumental cover that is actually phenomenal check out The Surfrajettes. Also amazing name.

I can’t make you love me by Bonnie Raitt

I recently found out about the Zelda: Link to the Past randomizer community. Essentially there is a method to modify the original game to randomize the item locations and other aspects of the game while ensuring the game can be completed. Each game has a seed so you can look it up if you get to stuck. I played through it once and it was a really interesting challenge since I didn’t get the bow until 60% of the way through the game.

On my 8th birthday my dad took a couple friends and I out to dinner and we stopped to buy a video game. My friends and I were arguing about what to get and my dad came by a couple times to get us to hurry up. Finally he said we had to make a decision and ushered us up to the cashier.

As soon as the cashier started to talk a truck off the highway that was above the store crashed through the side wall of the shop with enough speed to hit through every aisle and collapse all the shelving to the back as well as ripping down the ceiling. The guy was covered in blood and slumped over the wheel. No one was hurt in the store luckily, but we all would have been killed if we argued any longer in that aisle. My dad just got us into the car and we drove home. Afterward my dad would just downplay it whenever I would bring it up.

I got access to a really nice VR system through work and binged through Half Life Alyx. I was in a room that was large enough to walk around in, but for larger moves you use the controller to teleport a short distance. Also you can gravity attract items within a few yards with your gloves.

After playing the first time I went to cook dinner and got embarrassingly frustrated when I tried to summon a spoon with a hand gesture.

I played Like a Dragon with no background and it was a great experience. Really wacky in a satisfying way. Only grievance is there is ~10 hours of cut scenes to beat the game.

When I was in secondary school I had to fill out a form over the summer to be allowed to leave early for some school activities. The form required a coach or teacher’s signature. Since it was the summer, I had no contact with any faculty so I had my parents call the coach who told me to sign the form for him, which I did and I turned it in. Unfortunately, that coach left before the beginning of the year so when school started I was called to the principal’s office and accused of forging his signature. I told the principal the coach told me to, so it wasn’t a forgery, I was signing on his behalf, and I even put that on the form. He ended up calling the coach and he even confirmed but at that point he didn’t want to back down and still denied the request.

After I left the two older ladies that ran the office found me and told me they just approved it after he left for the day and he would never know. They were super nice and told me they were proud of me for sticking up for myself. As a barely out of primary school kid it was really intimidating to be yelled at by an adult but I felt so vindicated when they recognized the inequity of the situation and helped me.

That principal ended up only lasting a year too.

Depending on the complexity of the part either Fusion 360, Tinkercad, or even just 3d Builder. I usually can find something close already existing and just modify that.

As someone who has been in the 3d printing space for awhile, I am amazed at how cheap and featured the entry level printers are. For ~$150 you can get a printer with auto bed leveling and a magnetic bed. At $15/lb of filament, you only need a few projects to pay for itself.

For example, I printed the housing for a USB hub for a friend which is a clone for a ridiculously expensive one that fits Lovesac couches and he paid me $50. It cost ~$2 of filament and ended up printing a few more for others. That alone paid for the cost of the printer.

For anyone who is thinking about it, now is a great time to enter the hobby.

I commented this elsewhere, but to answer your question,

Zolgemsma is a modified version of adeno associated virus and has to be grown under specific conditions. It costs $500k-$1m per production. It’s also a one time injection that functionally cures the person of the disease. There are a couple other options but for comparison, the other therapeutic is Spinraza which is an intermittent intrathecal infusion which is $805,000 for the first year of therapy and $380,000 per year thereafter for the rest of your life.

SMA type I also is 100% fatal by year 2-3 and the baby dies without being able to even lift their head. It’s a terrible prognosis.

To be clear, I think we should bear the actual costs of research, development, and manufacture as a society and not profiteer off the sick, but there are some contributory reasons for the price.

Zolgemsma is a modified version of adeno associated virus and has to be grown under specific conditions. It costs $500k-$1m per production.. It’s also a one time injection that functionally cures the person of the disease. There are a couple other options but for comparison, the other therapeutic is Spinraza which is an intermittent intrathecal infusion which is $805,000 for the first year of therapy and $380,000 per year thereafter for the rest of your life.

To be clear, I think we should bear the actual costs of research, development, and manufacture as a society and not profiteer off the sick, but there are some contributory reasons for the price.

I would say Robin Hobb. She writes easy to read, character driven fantasy novels that gracefully deal with a gamut of difficult topics (e.g., orphanism, otherness, sexual violence, mortality, etc.). The books really helped me build empathy for people and concepts that were far afield of my own experience.

That’s true but the difference is exceedingly small.

According to 1 FDA study, the mean difference for AUC values between test and reference products was found to be 3.5% in the 2-year period following the Waxman-Hatch Act, and 80% of the absolute differences between generic products approved since 1984 and the corresponding innovator products were within a 5% range.

Debunking a Common Pharmacy Myth: The 80-125% Bioequivalence Rule Jun 8, 2016

The HIPAA Privacy Rule exception for law enforcement purposes, 45 CFR § 164.512(f), permits a covered entity (generally, healthcare providers, health plans and their business associates) to disclose PHI to law enforcement officials without patient authorization under certain circumstances.

Those pharmacies also have this exception listed in their Privacy Policy. I don’t like it either, but it is legal.

Oh, I agree. I use a different printer now too for most things but I still have the original one. The technology has really advanced in the intervening years.

Ender 3 3d printer about 6 years ago. I bought it used for $100 on a whim with no knowledge on how to use one. Now it’s the most useful tool in my house. Need a slightly bigger hollow wall anchor? You can print one. Custom desk organizer? Print one. Name plates for a dinner party. Stamp to impress into wax or leather. Fantasy scatter terrain.

There is certainly a learning curve but if you can get proficient you can make countless helpful things that would would not be able to buy.